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pentobarbital will decrease the level or effect of mestranol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will minimize the level or effect of quinine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.Watch Intently (1)pentobarbital will reduce the level or effe